Subject: Nature Contents: 17 March 2005 Volume 434 No. 7031 pp257-420

From: "NatureAlert"<[email-masked]>
Date: Wed, 16 Mar 2005 13:41:57 -0500 (EST)

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17 March 2005

Editorials
News
News Feature
Correspondence
Books and Arts
The Physics Detective
News and Views
Brief Communications
Artists on science: scientists on art
Articles
Letters to Nature
Naturejobs
Futures

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Feature of the week

Web focus: The X chromosome
The human X chromosome is a study in contradictions. The detailed sequence of the X published in this issue, and a survey of inactivated genes in females, help to illuminate this unique "evolutionary space". This completed sequence, the 14th human chromosome to be published in Nature, is accompanied online with a collection of classic papers from Nature and Nature Genetics.

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| Editorials |

Politics versus reality 257
Japan's politicians have to face scientific uncertainty, no matter how uncomfortable it may be. They should mobilize diplomatic means, and not sacrifice scientific integrity, in their fight with North Korea.
doi:10.1038/434257a
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Nature respects preprint servers 257
... despite false rumours to the contrary.
doi:10.1038/434257b
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| News |

Indian regulations fail to monitor growing stem-cell use in clinics 259
India's science and health ministries are to cooperate on guidelines.
doi:10.1038/434259a
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Rugby team converts to give gene tests a try 260
Australian club wins advantage through genetically tailored training.
doi:10.1038/434260a
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Japan plans blood-donor restrictions to combat vCJD 260
First death prompts proposal that may create blood shortage.
doi:10.1038/434260b
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Bush settles on technical innovator to head up NASA 261
Pioneer of small, smart missions picked to run US space agency.
doi:10.1038/434261a
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Global bomb-test monitor could give tsunami warnings 261
Critics fear use of politically sensitive data.
doi:10.1038/434261b
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Fallout of fertilizers set too low, studies warn 262
Greenhouse-gas levels may be seriously underestimated.
doi:10.1038/434262a
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Gene tests served up to tell fine foods from fakes 262
Japan plans to ensure local delicacies are the real thing.
doi:10.1038/434262b
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Plans for research watchdog praised, but it may lack teeth 263
Panel to oversee British biomedical science sparks controversy.
doi:10.1038/434263a
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Row flares over attempt to dilute radioactive waste 263
Proposal for burying cold-war nuclear waste in concrete faces scrutiny.
doi:10.1038/434263b
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news in brief 264
doi:10.1038/434264a
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| News Feature |

Genetics: The X factor 266
The sequence of the 'feminine' X chromosome is a prime hunting ground for geneticists interested in the evolution of the cognitive and cultural sophistication that defines the human species. Erika Check reports.
doi:10.1038/434266a
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Primate research: Die hard 268
Grenada's monkeys have thrived despite a huge degree of inbreeding. But now they face a new genetic bottleneck in the wake of Hurricane Ivan. Sharon Levy investigates.
doi:10.1038/434268a
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| Correspondence |

NIH must tell whole truth about conflicts of interest 271
Little has yet been disclosed about a consulting spree that has left a legacy of harm.
doi:10.1038/434271a
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Limits to growth may be subtle but still inexorable 271
doi:10.1038/434271b
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More power needed to probe cloud systems 271
doi:10.1038/434271c
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| Books and Arts |

Just for fun? 273
BERND HEINRICH reviews The Genesis of Animal Play: Testing the Limits by Gordon M. Burkhardt
Working out why animals play is no easy task.
doi:10.1038/434273a
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To infinity and beyond! 274
DAVID LINDLEY reviews Parallel Worlds: The Science of Alternative Universes and Our Future in the Cosmos by Michio Kaku
doi:10.1038/434274a
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A chemical conspiracy? 275
JAMES CLARK reviews The Fluoride Deception by Christopher Bryson
doi:10.1038/434275a
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New in paperback 275
doi:10.1038/434275b
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| The Physics Detective |

Schrödinger's mousetrap 277
PETER TUTHILL
Part 9: Out in the cold.
doi:10.1038/434277a
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| News and Views |

Genome biology: She moves in mysterious ways 279
CHRIS GUNTER
The human X chromosome is a study in contradictions. The detailed sequence of the X, and a survey of inactivated genes in females, help to illuminate this unique 'evolutionary space'.
doi:10.1038/434279a
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Planetary science: Picturing a recently active Mars 280
VICTOR R. BAKER
Discoveries made with the High Resolution Stereo Camera on the Mars Express orbiter show that, as recently as a few million years ago, the surface of Mars was being shaped by flowing water, lava and ice.
doi:10.1038/434280a
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Evolution: Deep-sea spiral fantasies 283
JOHN GAGE
Pictures of strange, gelatinous deep-sea worms have intrigued zoologists, as they hinted at the solution to an evolutionary puzzle. But does the first specimen to be obtained in good condition back the theories up?
doi:10.1038/434283a
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100 and 50 years ago 284
doi:10.1038/434284a
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Applied physics: Electrons held in a queue 285
DMITRI V. AVERIN
When electric currents are made sufficiently small, the electrons can be seen moving one by one. This is accomplished in a microelectronic circuit, providing a means of obtaining an accurate standard for current.
doi:10.1038/434285a
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Cancer biology: Sense out of missense 287
TERRY VAN DYKE
The p53 protein is notorious for its involvement in many cancers. Studies in mice are helping to clarify how mutations in the human p53 protein produce a wide variety of tumours.
doi:10.1038/434287a
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Human genomics: Disclosure of variation 288
RASMUS NIELSEN
Now that the sequence of the human genome is almost complete, the human genomics community is turning its attention towards what, genetically speaking, makes people different.
doi:10.1038/434288a
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Language: Syntax for free? 289
RICARD SOLÉ
Human language is based on syntax, a complex set of rules about how words can be combined. In theory, the emergence of syntactic communication might have been a comparatively straightforward process.
doi:10.1038/434289a
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research highlights 290
doi:10.1038/434290a
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| Brief Communications |

Indonesian earthquake: Earthquake risk from co-seismic stress 291
JOHN MCCLOSKEY, SULEYMAN S. NALBANT & SANDY STEACY
Last year's Indonesian earthquake has increased seismic hazard in the region.
doi:10.1038/434291a
First paragraph | Full Text

Biomechanics: Independent evolution of running in vampire bats 292
DANIEL K. RISKIN AND JOHN W. HERMANSON
doi:10.1038/434292a
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| Artists on science: scientists on art |

Editorial 293
ALISON ABBOTT AND ADAM RUTHERFORD
doi:10.1038/434293a
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Fiction informed by science 294
A. S. Byatt's encounters with science shape the story and characters in her four-part series of novels.
doi:10.1038/434294a
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Science in literature 297
Simon Mawer crosses the divide to explore how scientists and novelists alike grapple with an uncertain world.
doi:10.1038/434297a
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A tale of two loves 299
The arts and sciences provide complementary ways of looking at the world, argues Alan Lightman.
doi:10.1038/434299a
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The artist as neuroscientist 301
PATRICK CAVANAGH
Artistic licence taps into the simplified physics used by our brain to recognize everyday scenes, says Patrick Cavanagh.
doi:10.1038/434301a
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From science in art to the art of science 308
MARTIN KEMP
Shared intuitions about the natural world drive the pursuits of artists and scientists, says Martin Kemp.
doi:10.1038/434308a
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Experimental physics, experimental art 310
KEN MCMULLEN
What happens when artists and particle physicists are brought together to exchange ideas? Ken McMullen describes the creative fallout.
doi:10.1038/434310a
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Music, the food of neuroscience? 312
ROBERT ZATORRE AND JAMES MCGILL
Playing, listening to and creating music involves practically every cognitive function. Robert Zatorre explains how music can teach us about speech, brain plasticity and even the origins of emotion.
doi:10.1038/434312a
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The evolution of sensibility 316
COMPOSER ROGER REYNOLDS
Understanding the science behind aesthetic perception could guide and restrain the 'shock of the new' approach to music. Composer Roger Reynolds explains how.
doi:10.1038/434316a
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Poetry and science: greatness in little 320
PETER FORBES
Peter Forbes explores how poetry and science can mutually inspire.
doi:10.1038/434320a
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| Articles |

The DNA sequence of the human X chromosome 325
MARK T. ROSS, et al.
doi:10.1038/nature03440
Summary | Full Text

Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals 338
XIAOHUI XIE, JUN LU, E. J. KULBOKAS, TODD R. GOLUB, VAMSI MOOTHA, KERSTIN LINDBLAD-TOH, ERIC S. LANDER & MANOLIS KELLIS
doi:10.1038/nature03441
Summary | Full Text

Tropical to mid-latitude snow and ice accumulation, flow and glaciation on Mars 346
J. W. HEAD, et al.
doi:10.1038/nature03359
Summary | Full Text

| Letters to Nature |

Evidence from the Mars Express High Resolution Stereo Camera for a frozen sea close to Mars' equator 352
JOHN B. MURRAY, et al.
doi:10.1038/nature03379
First paragraph | Full Text

Discovery of a flank caldera and very young glacial activity at Hecates Tholus, Mars 356
ERNST HAUBER, et al.
doi:10.1038/nature03423
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Current measurement by real-time counting of single electrons 361
JONAS BYLANDER, TIM DUTY & PER DELSING
doi:10.1038/nature03375
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Relaxor ferroelectricity and colossal magnetocapacitive coupling in ferromagnetic CdCr2S4 364
J. HEMBERGER, et al.
doi:10.1038/nature03348
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Two-electron dissociation of single molecules by atomic manipulation at room temperature 367
P. A. SLOAN AND R. E. PALMER
doi:10.1038/nature03385
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Subducted banded iron formations as a source of ultralow-velocity zones at the core–mantle boundary 371
DAVID P. DOBSON AND JOHN P. BRODHOLT
doi:10.1038/nature03430
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'Lophenteropneust' hypothesis refuted by collection and photos of new deep-sea hemichordates 374
NICHOLAS D. HOLLAND, et al.
doi:10.1038/nature03382
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Ancient co-speciation of simian foamy viruses and primates 376
WILLIAM M. SWITZER, et al.
doi:10.1038/nature03341
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Genetic relatedness predicts South African migrant workers' remittances to their families 380
S. BOWLES AND D. POSEL
doi:10.1038/nature03420
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Genetic effects on sperm design in the zebra finch 383
T. R. BIRKHEAD, E. J. PELLATT, P. BREKKE, R. YEATES & H. CASTILLO-JUAREZ
doi:10.1038/nature03374
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Optimal eye movement strategies in visual search 387
JIRI NAJEMNIK AND WILSON S. GEISLER
doi:10.1038/nature03390
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The first cleavage of the mouse zygote predicts the blastocyst axis 391
BERENIKA PLUSA, et al.
doi:10.1038/nature03388
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The MET oncogene drives a genetic programme linking cancer to haemostasis 396
CARLA BOCCACCIO, et al.
doi:10.1038/nature03357
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X-inactivation profile reveals extensive variability in X-linked gene expression in females 400
LAURA CARREL AND HUNTINGTON F. WILLARD
doi:10.1038/nature03479
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The vacuolar Ca2+-activated channel TPC1 regulates germination and stomatal movement 404
EDGAR PEITER, et al.
doi:10.1038/nature03381
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Molecular determinants and guided evolution of species-specific RNA editing 409
ROBERT A. REENAN
doi:10.1038/nature03364
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Erratum : Pleistocene to Holocene extinction dynamics in giant deer and woolly mammoth 413
A. J. STUART, P. A. KOSINTSEV, T. F. G. HIGHAM & A. M. LISTER
doi:10.1038/nature03413
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| Researcher | | Bioinformatics|Chemistry|Materials Science|Medicinal & Pharm. Chem.|Pharmacology| | | University of Anglia | | Norwich, United Kingdom
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Postdocs, mentor thyselves 415
PAUL SMAGLIK
doi:10.1038/nj7031-415a
Full Text

Make your point 416
KENDALL POWELL
Engaging presentations can land jobs and increase visibility. Kendall Powell learns the art of a good talk.
doi:10.1038/nj7031-416a
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Career View 418
doi:10.1038/cv7031
Full Text

Graduate Journal: Writer's block 418
ANNE MARGARET LEE
doi:10.1038/nj7031-418a
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Scientists & Societies 418
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doi:10.1038/nj7031-418b
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Movers 418
doi:10.1038/nj7031-418c
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| Futures |

Last man standing 420
XAVIERA YOUNG
Whatever happened to 'boy meets girl'?
doi:10.1038/434420a
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