Subject: Supplemental Vitamin E and Heart Failure Risk

From: "Medscape Week in Review"<[email-masked]>
Date: Tue, 22 Mar 2005 17:44:59 -0500 (EST)

| | www.medscape.com/today |

SEARCH

|

| Medscape

| MEDLINE

| DrugInfo

Advertisement - Metastatic Breast Cancer Treatment
Learn more about a new path to superior outcomes with first-line therapy.

Alemtuzumab as an induction or preconditioning agent in kidney transplantation

CKD: Managing CV Complications

Patient Education

Find Resources For Your Patients

Member Benefits

Medscape Members: save up to $50 on ACP Medicine
The Most Current Internal Medicine Textbook Available Anywhere

Contact Us

Editorial Comments
Mindy Hung
[email-masked]

Technical Support
[email-masked]

Mailing Address
WebMD Medscape
Attn: email newsletters
224 W. 30th Street
New York, NY 10001

Advertisement - Pharmacokinetics Of Transdermal Contraceptive
Review time-concentration profiles of the once-weekly transdermal birth control patch.

Top Stories

Supplemental Vitamin E May Increase Heart Failure Risk

Conference Coverage -- Nurse Practitioners in Women's Health Conference

Bird Flu Clusters May Signal Virus Change: WHO

Browse | | Medscape Content by Topic

Feature Articles

Instant Poll
Roe v. Wade Case to Remain Closed
In a Medscape Instant Poll that launched March 15, 74% of respondents agreed with the recent US Supreme Court decision not to reopen Roe v. Wade. But 25% disagreed with the decision. As of March 17, a total of 691 respondents had taken part in this poll. To view the full results of the poll, which ended on March 22, click on the title above.

Letters
Readers' Responses to "Caution -- Lab Test Ordering Trouble Ahead"
Are physicians too dependent on tests? Readers weigh in.
Medscape General Medicine 7(1) 2005

Allergy/Clinical Immunology
Treating ImmunoglobulinE Syndrome
I have a 6-year-old patient with IgE levels of 10,000 U. The main presenting problem is skin infections. What would be your treatment recommendation for this patient?
Medscape Allergy & Clinical Immunology 5(1) 2005

Business of Medicine
Strategies to Enhance Patient Adherence: Making It Simple
How can providers become more familiar with proven interventions that can enhance patient adherence?
Medscape General Medicine 7(1) 2005

The American Healthcare "System" in 2005 -- Part 7: A Public-Private Mix
Dr. Lundberg offers his solution to the healthcare dilemmas that we now face -- a public-private mix of funding and caregivers, with a heavy dose of individuality.

Medicare as a Catalyst For Reducing Health Disparities
Medicare has played some role in reducing health disparities but has not yet realized its potential.

Cardiology
TNT: Treating to New Targets
ACC'05: The evidence continues to accumulate that when it comes to LDL cholesterol, "lower is better" -- but how do we achieve that?

COMPASS-HF: Chronicle Offers Management to Patients With Advanced Signs and Symptoms of Heart Failure Study
ACC '05: Optimal medical care guided by an implantable device that continuously monitors intracardiac pressures shows promise in reducing morbidity in HF patients.

ASCOT-BPLA: Blood Pressure-Lowering Arm of the Anglo-Scandinavian Cardiac Outcomes Trial
ACC'05: Another -- although perhaps not the last -- proof that the "newer" antihypertensive treatment strategy of CCB plus ACE inhibitor is better than beta-blocker plus diuretic for cardioprotection.

Critical Care
Erythropoietin Response in Critically Ill Mechanically Ventilated Patients
An examination of the erythropoietic response to anemia in the critically ill mechanically ventilated patient.
Crit Care 9(3) 2005

Dermatology
Atopic Dermatitis and the 'Hygiene Hypothesis': Too Clean to be True?
The "hygiene hypothesis" postulates an inverse relationship between atopic dermatitis and an environment that leads to increased pathogen exposure.
Br J Dermatol 152(2) 2005

Twenty-Nail Dystrophy Originating From Lichen Planus
A 6-year-old boy comes to the clinic with grubby, rough, and brittle nails.

Diabetes & Endocrinology
Vitamin D and the Elderly
Review current knowledge on vitamin D status in the elderly, with special attention to relationships between vitamin D status and various diseases common in the elderly.
Clin Endocrinol 62(3) 2005

Sphingolipids, Type 2 Diabetes, Metabolic Syndrome X, and Cushing's Syndrome
Is there a common molecular mechanism?

Family Medicine/Primary Care
Low Target Blood Pressure May Slow Progression of Nondiabetic Kidney Disease
Long-term follow-up of the Modification of Diet in Renal Disease Study showed that low target BP slowed progression in patients with moderately to severely decreased glomerular filtration rate.
Medscape Medical News2005

Alcohol-Related Injuries: Evidence for the Prevention Paradox
Risk of injury increases exponentially with alcohol consumption on a given occasion, but the conclusion that alcohol-related injuries are attributable primarily to heavy drinking may not be correct.

Gastroenterology
Enteral Feeding
Enteral nutrition is now widely used as the preferred route of nutritional support in malnourished and intensive care unit patients.
Curr Opin Gastroenterol 21(1) 2005

Systematic Review: The Liver in Coeliac Disease
There is growing evidence that a largely silent chronic liver abnormality -- cryptogenic-elevated transaminases -- is frequently associated with untreated celiac disease.

General Surgery
Selective Gastrointestinal Tract Decontamination May Be Helpful in Burn Patients
In a randomized trial, this procedure reduced mortality and pneumonia incidence.
Medscape Medical News2005

Intermittent Pneumatic Compression of the Foot and Calf May Help in Arterial Claudication
In a randomized study, this modality significantly improved walking distance and quality of life.

HIV/AIDS
Antiretroviral Therapy and Cardiovascular Risk: An Expert Interview With Richard Elion, MD
Management of cardiovascular and metabolic risks has emerged as a critical task for HIV specialists. Learn the latest about this topic from a clinical expert.
Medscape HIV/AIDS 11(1) 2005

Alendronate May Be Helpful for HIV-Associated Osteopenia and Osteoporosis
In a randomized study, this drug combined with vitamin D and calcium was safe and increased lumbar spine bone mineral density by about 5% at 48 weeks.

Pregnancy and Other Factors Associated With Higher CD4+ T-Cell Counts at HIV Diagnosis
The impact of routine screening of pregnant women and other factors on the stage of HIV disease at diagnosis were evaluated.

Hematology-Oncology
Topics in Pediatric Leukemia -- Myelodysplastic and Myeloproliferative Disorders of Childhood
A recent classification addresses specific diagnostic problems and the rarity of specific disease entities in children.
Medscape General Medicine 7(1) 2005

Genotype of Metabolic Enzymes and the Benefit of Tamoxifen in Postmenopausal Breast Cancer Patients
Is there a relationship between tamoxifen resistance and differences in activity of metabolic enzymes due to genetic polymorphism?

Infectious Diseases
Bird Flu Clusters May Signal Virus Change: WHO
A cluster of human bird flu cases among relatives and possibly health workers in Vietnam may show the virus is changing into a form that can be passed on by humans, the World Health Organization said.
Reuters Health Information2005

A Case of Brucella Spondylodiscitis With Extended, Multiple-Level Involvement
A 61-year-old man had a 2-month history of fever, chills, and profuse sweating, especially at night.

Border Screening for SARS
How effective is screening for SARS at international borders? This review of the Canadian screening process offers some insight.

Internal Medicine
Supplemental Vitamin E May Increase Heart Failure Risk
In the HOPE-TOO trial, vitamin E did not reduce the risk of cancer or major cardiovascular events.
Medscape Medical News2005

Treatment of Depression Improves Physical Functioning in Older Adults
This randomized study demonstrates improved physical function in older depressed patients who responded to collaborative care management for depression.

Neurology & Neurosurgery
The Current State of Pain Management: An Expert Interview With Scott M. Fishman, MD
At the 21st Annual Meeting of AAPM, Medscape spoke to the academy's incoming president, Scott M. Fishman, MD, about the current state of pain management.
Medscape Neurology & Neurosurgery 7(1) 2005

Rasagiline and Entacapone May Be Similarly Effective in Parkinson's Disease
In a short but large study, once-daily rasagiline reduced mean daily off-time and improved symptoms in levodopa-treated patients with motor fluctuations.

Self-Reported Headache Frequency in Canadian Adolescents: Validation and Follow-Up
Headaches cause significant morbidity in childhood. This study examined the prevalence and associated factors of frequent headache in a new sample of Canadian youth, to validate previous findings.

Nursing
Conference Coverage -- Nurse Practitioners in Women's Health Conference
Key conference highlights from NPWH include pregnancy and childbirth, genetics, menopause management, complementary therapies, depression, and more.

Using Empowerment to Build Trust and Respect in the Workplace
Lack of trust and respect in the workplace has negative effects on both the organization and the employees.

Overlapping Conditions in Women With Irritable Bowel Syndrome
More attention should be focused on comorbid conditions such as chronic pelvic pain and interstitial cystitis in patients with IBS.

Ob/Gyn and Women's Health
Laparoscopic Ovarian Transposition to Preserve Ovarian Function Before Pelvic Radiation and Chemotherapy
Ovarian transposition is an effective surgical procedure in patients at risk of radiotherapy-induced ovarian failure.
Medscape General Medicine 7(1) 2005

Pre-eclampsia Community Guideline Based on National Institute for Clinical Excellence Recommendations
The editorialist said that PRECOG was simple, evidence based, and should be used; and an accompanying systematic review of controlled studies summarized risk factors for preeclampsia.

Conference Report -- Society of Maternal-Fetal Medicine 24th Annual Clinical Meeting
This report focuses on some of the key presentations made in the fields of preterm delivery and prenatal aneuploidy screening as well as in clinical obstetrics.

Orthopaedics
Physical Activity Profiles of U.S. Adults Trying to Lose Weight: NHIS 1998
Despite the importance of physical activity in a weight loss program, only about half of the individuals in this study who were trying to lose weight reported using exercise.
Med Sci Sports Exerc 37(3) 2005

Journal Scan
This month's scan centers on minimally invasive hip replacement techniques, the management of femoral fractures, and the risk of infection associated with allogeneic or autologous blood components.

Pathology & Lab Medicine
A 14-Year-Old Male With Abdominal Pain
Subjective recurrent low-grade fevers, epigastric abdominal pain associated with a 10-pound weight loss. Symptoms began 2 weeks after a camping trip.
Lab Med 36(3) 2005

Medicare Policy in 2005: Physician Reimbursement Crisis Raises Additional Issues
When it comes to fixing the sustainable growth rate (SGR) formula used to set Medicare's physician reimbursement rates, a dose of reality is about to dawn on Washington policy circles.

Pediatrics
Fatal Hypermagnesemia Caused by an Epsom Salt Enema: A Case Illustration
A 7-year-old male with a history of constipation presented to an outside hospital with cardiopulmonary arrest.
South Med J 98(2) 2005

Pharmacist
Avonex Linked to Rare Reports of Severe Hepatic Injury, Failure
Interferon beta-1a may cause severe hepatic injury or failure, and a new registry is being created for women who become pregnant during treatment, according to the FDA.
Medscape2005

Quality of Generic Clarithromycin Products From 18 Countries
Are the European-manufactured generic agents equivalent to the branded product?

Daily OK, But Q.D. Is Not
Recent safety alerts regarding prescribing Palladone and Avinza.

Psychiatry
Clozapine May Be Effective in Reducing Violent Behaviors
A chart review suggests that clozapine effectively reduces violent behaviors regardless of underlying psychiatric diagnosis.
Medscape Medical News2005

Early Detection of Schizophrenia
How can schizophrenia's prodromes be detected so that the duration of untreated psychosis and distress is minimized?

Public Health & Prevention
Mercury in Commercial Fish: Optimizing Individual Choices to Reduce Risk
Significant species differences and significant differences in availability and in mercury levels among fish and shellfish were found in this investigation conducted in New Jersey.
Environ Health Perspect 113(3) 2005

Pulmonary Medicine
Is a Long-Acting Inhaled Bronchodilator the First Agent to Use in Stable Chronic Obstructive Pulmonary Disease?
Should a long-acting inhaled bronchodilator be the initial choice for maintenance therapy in patients with stable, symptomatic chronic obstructive pulmonary disease?
Curr Opin Pulm Med 11(2) 2005

Rheumatology
Infusion Reactions With Anti-Tumor Necrosis Factor Blockers
Could therapy with anti-tumor necrosis factor-alpha blockers or anti-CD20 antibodies induce infusion reactions in an IgA-deficient lupus patient?
Medscape Rheumatology 6(1) 2005

Gastrin-Releasing Peptide and Substance P and Levels of Cytokines in Rheumatoid Arthritis
This study investigates the therapeutic potential of targeting neuropeptides in RA.

Failing Response to Infliximab
A 29-year-old male patient with psoriatic arthritis and skin involvement had poor response to last infusion of infliximab.

Urology
Quality-of-Life Utility Values for Erectile Function and Sildenafil Treatment
Is the quality of life gained by the drug worth the cost?
Clin Drug Invest 25(2) 2005

Relationship Between Smoking and Erectile Dysfunction
Although smoking seems to cause ED and ED seems to cause smoking, the increases in risk were relatively small.

What Are The Latest Advances In The Treatment of Colorectal Cancer?
Colorectal cancer is the third most common cancer and it accounts for about 10% of all cancer deaths. Read about the latest strides in the prevention, diagnosis, and treatment of colorectal cancer in Medscape.com's Colorectal Cancer Resource Center.

How Can You Better Diagnose And Manage Insomnia in Your Patients?
Despite its high prevalence, insomnia is often misunderstood and mismanaged, which can lead to severe consequences. To learn more about this complex problem that affects tens of millions of people, visit the Insomnia and Sleep Health Resource Center.

Product Spotlight
Product Information from Industry

LOTREL® (amlodipine besylate/benazepril HCI) - Important findings, safety information, full Prescribing Information available here.

Namenda® (memantine hydrochloride) - Indicated for the treatment of moderate to severe dementia of the Alzheimer's type. Review clinical findings, read full Prescribing Information.

St. Jude Medical Advanced Solutions for Cardiac Rhythm Disorders InfoSite - Get the latest on Heart Failure and Atrial Fibrillation therapies and devices, technical insights, patient information, and more.

User Support

Unsubscribe from this newsletter

Subscribe to this newsletter

Not yet a Medscape member?

Forgot your login info?

Add MedPulse to your email 'Safe List' or Personal Address Book

Cannot read this newsletter? Prefer the TEXT version?
http://mp.medscape.com/cgi-bin1/DM/y/hnFh0EM6CR0Dyr0FqjA0Ez

Difficulty linking to a news story?

Difficulty Viewing Images?

Need additional support?

Note for AOL subscribers: To unsubscribe from this newsletter, please click on the unsubscribe link above rather than clicking on the "Report Spam" button in your AOL inbox. If you have difficulty unsubscribing, please contact Medscape directly at [email-masked].

To remove your address from all Medscape mailing lists, please write to us at [email-masked].