Subject: Drug Discovery@nature 13 October 2006

From: "Drug Discovery Alert"<[email-masked]>
Date: Fri, 13 Oct 2006 08:38:47 -0400 (EDT)

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13 October 2006 Issue

News

Research highlights

Research & reviews

Market analysis

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This eTOC alert is supported by
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Nature Reviews Therapeutic proteins collection
October 2006

Nature Reviews presents a Therapeutic proteins collection, which includes Research Highlights, Reviews and Perspectives articles from Nature Reviews Drug Discovery, Nature Reviews Cancer and Nature Reviews Immunology.

This Collection highlights our current understanding of the design, generation and application of proteins as therapeutics, and will be free online for six months with generous support from Invitrogen.

Visit www.nature.com/reviews/focus/therapeuticproteins

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| News |

Depression genes show when the drugs won't work
Anxious mice could point to better treatment for human conditions.

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Nobel prize blurs boundaries
"But is it chemistry?" ask chemists.

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AIDS in Africa: A question of trust
AIDS treatment in South Africa is often a tug-of-war between clinicians and traditional healers. Natasha Bolognesi meets a woman who is uniquely qualified to heal the rift.

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Youthful duo snags a swift Nobel for RNA control of genes
Award comes just eight years after publication.

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more news

| Research highlights |

Psychiatric disorders: ProTREKtion against depression
A potassium channel could be a potential target for novel antidepressants.

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Ageing: Longevity mutations inhibit tumours
Findings extend link between aging and cancer.

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Malaria: Hepatic highlights
New imaging tool should boost use of malaria model to study infections.

more research highlights

| Market analysis |

From the Analyst’s Couch: Life after statin patent expiries
The future of the cholesterol-lowering market.

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From the pipeline: Ranibizumab
New anti-angiogenic therapy for age-related macular degeneration.

more market analysis articles

| Research & reviews |

Discovery and development of sorafenib
The story behind the first multikinase inhibitor for cancer.

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Impact of microarray data quality on genomic data submissions to the FDA
How can microarray data best be exploited and integrated into the regulatory decision-making process?

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How will HPV vaccines affect cervical cancer?
The ramifications and questions surrounding these preventive vaccines.

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Dynamic modeling of imatinib-treated chronic myeloid leukemia: functional insights and clinical implications
Mathematical modeling approach examines the therapeutic effect of targeted drug.

more research & reviews

| Naturejobs drug discovery |

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William Keller
How to successfully form collaborations in China.

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