Subject: Nature Biotechnology Contents: October 2006 Volume 24 pp. 1177 - 1298

From: "Nature Biotechnology Alert"<[email-masked]>
Date: Wed, 11 Oct 2006 12:50:02 -0400 (EDT)

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October 2006, Volume 24 No 10

| In This Issue

| Editorials

| News: In Brief | Data Page | News Feature

| Bioentrepreneur: Building a business

| Opinion and Comment: Correspondence | Commentary | Investor's Lab | Book Review

| Features: Patents

| News and Views

| Computational Biology: Analysis

| Research: Perspective | Brief Communications | Articles | Letters | Erratum | Corrigenda

| Naturejobs: Careers and Recruitment | People

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Community Consultation

Various scientific communities are engaged in producing data-reporting standards similar to the MIAME guidelines for microarray data. Some of these papers are under consideration for publication in Nature Biotechnology.

To encourage broad participation in the standards-development process, we are making the papers freely available at www.nature.com/nbt/consult/index and we urge you to participate and send us your comments and suggestions, which will be carefully considered by the authors, reviewers and editors.

In This Issue

Top

PDF

Editorials

Top

Why silence is not an option p1177

doi:10.1038/nbt1006-1177

Abstract | Full Text | PDF

Parallel universes? p1178

doi:10.1038/nbt1006-1178a

Abstract | Full Text | PDF

Partnering with a difference p1178

doi:10.1038/nbt1006-1178b

Abstract | Full Text | PDF

News

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Genentech raises stakes on PARP inhibitors pp1179 - 1180

Cormac Sheridan

doi:10.1038/nbt1006-1179

Full Text | PDF

Polyclonal antibodies step out of the shadows p1181

Emily Waltz

doi:10.1038/nbt1006-1181

Full Text | PDF

Poor enforcement could jeopardize China's drug innovation policy pp1182 - 1183

Hepeng Jia

doi:10.1038/nbt1006-1182

Full Text | PDF

Brazil next biotech trailblazer in Latin America? p1184

Ricardo Bonalume

doi:10.1038/nbt1006-1184

Full Text | PDF

In Brief

News In Brief pp1186 - 1187

doi:10.1038/nbt1006-1186

Full Text | PDF

Profile: Michael Fernandez p1188

Kendall Powell

doi:10.1038/nbt1006-1188

Abstract | Full Text | PDF

Data Page

Biotech patenting upturn p1190

Stacy Lawrence

doi:10.1038/nbt1006-1190

Full Text | PDF

News Feature

Turning plants into protein factories pp1191 - 1193

Jeffrey L Fox

doi:10.1038/nbt1006-1191

Abstract | Full Text | PDF

Bioentrepreneur

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Building a business

Exit strategies in Europe pp1195 - 1197

Peter Buckel, Ulrich Dauer, Patrik Frei & Jean-Yves Nothias

doi:10.1038/bioent911

PDF

Opinion and Comment

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Correspondence

Reactions to Eprex's adverse reactions pp1199 - 1200

Basant Sharma, Mary H. Ryan & Katia Boven

doi:10.1038/nbt1006-1199

Full Text | PDF

Reply to Reactions to Eprex's adverse reactions p1200

doi:10.1038/nbt1006-1200a

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Potential impact and cost-effectiveness of Golden Rice pp1200 - 1201

Alexander J Stein, H.P.S. Sachdev & Matin Qaim

doi:10.1038/nbt1006-1200b

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Commentary

The imitation game[mdash]a computational chemical approach to recognizing life pp1203 - 1206

Leroy Cronin, Natalio Krasnogor, Benjamin G Davis, Cameron Alexander, Neil Robertson, Joachim H G Steinke, Sven L M Schroeder, Andrei N Khlobystov, Geoff Cooper, Paul M Gardner, Peter Siepmann, Benjamin J Whitaker & Dan Marsh

doi:10.1038/nbt1006-1203

Abstract | Full Text | PDF

Investor's Lab

Biotech buybacks[mdash]good or bad? p1207

Tom Jacobs

doi:10.1038/nbt1006-1207

Full Text | PDF

Book Review

Relighting the Enlightenment p1209

Reviewed by: Simon G Best

doi:10.1038/nbt1006-1209

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Features

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The emerging nanomedicine landscape pp1211 - 1217

Volker Wagner, Anwyn Dullaart, Anne-Katrin Bock & Axel Zweck

doi:10.1038/nbt1006-1211

Abstract | Full Text | PDF

Patents

Biotech patents and the inequitable conduct doctrine pp1219 - 1221

Anthony Michael

doi:10.1038/nbt1006-1219

Abstract | Full Text | PDF

Recent patent applications in protein purification p1222

doi:10.1038/nbt1006-1222

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News and Views

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Putting proteins on the map pp1223 - 1224

Robert F Murphy

doi:10.1038/nbt1006-1223

Abstract | Full Text | PDF

See also: Research by Schubert et al.

Complementary therapies for inflammation pp1224 - 1226

Yi Wang

doi:10.1038/nbt1006-1224

Abstract | Full Text | PDF

See also: Research by Lee et al.

Automated phosphorylation site mapping pp1226 - 1227

Ole N Jensen

doi:10.1038/nbt1006-1226

Abstract | Full Text | PDF

See also: Research by Beausoleil et al.

Deciphering bioplastic production pp1227 - 1229

Sang Yup Lee

doi:10.1038/nbt1006-1227

Abstract | Full Text | PDF

See also: Research by Pohlmann et al.

Wastewater genomics pp1229 - 1230

Takashi Mino & Hiroyasu Satoh

doi:10.1038/nbt1006-1229

Abstract | Full Text | PDF

See also: Research by Martin et al.

A sugar switch for anti-inflammatory antibodies pp1230 - 1231

Roy Jefferis

doi:10.1038/nbt1006-1230

Abstract | Full Text | PDF

Research Highlights p1233

doi:10.1038/nbt1006-1233

Full Text | PDF

Computational Biology

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Analysis

Deviant effects in molecular reaction pathways pp1235 - 1240

Michael S Samoilov & Adam P Arkin

doi:10.1038/nbt1253

Abstract | Full Text | PDF

Research

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Perspective

Post-translational modifications in the context of therapeutic proteins pp1241 - 1252

Gary Walsh & Roy Jefferis

doi:10.1038/nbt1252

Abstract | Full Text | PDF

Brief Communications

Protein chip fabrication by capture of nascent polypeptides pp1253 - 1254

Sheng-Ce Tao & Heng Zhu

doi:10.1038/nbt1249

Abstract | Full Text | PDF

Efficient enucleation of erythroblasts differentiated in vitro from hematopoietic stem and progenitor cells pp1255 - 1256

Kenichi Miharada, Takashi Hiroyama, Kazuhiro Sudo, Toshiro Nagasawa & Yukio Nakamura

doi:10.1038/nbt1245

Abstract | Full Text | PDF

Articles

Genome sequence of the bioplastic-producing [ldquo]Knallgas[rdquo] bacterium Ralstonia eutropha H16 pp1257 - 1262

Anne Pohlmann, Wolfgang Florian Fricke, Frank Reinecke, Bernhard Kusian, Heiko Liesegang, Rainer Cramm, Thomas Eitinger, Christian Ewering, Markus Potter, Edward Schwartz, Axel Strittmatter, Ingo Vosz, Gerhard Gottschalk, Alexander Steinbuchel, Barbel Friedrich & Botho Bowien

doi:10.1038/nbt1244

Abstract | Full Text | PDF

See also: News and Views by Lee

Metagenomic analysis of two enhanced biological phosphorus removal (EBPR) sludge communities pp1263 - 1269

Hector Garcia Martin, Natalia Ivanova, Victor Kunin, Falk Warnecke, Kerrie W Barry, Alice C McHardy, Christine Yeates, Shaomei He, Asaf A Salamov, Ernest Szeto, Eileen Dalin, Nik H Putnam, Harris J Shapiro, Jasmyn L Pangilinan, Isidore Rigoutsos, Nikos C Kyrpides, Linda Louise Blackall, Katherine D McMahon & Philip Hugenholtz

doi:10.1038/nbt1247

Abstract | Full Text | PDF

See also: News and Views by Mino and Satoh

Analyzing proteome topology and function by automated multidimensional fluorescence microscopy pp1270 - 1278

Walter Schubert, Bernd Bonnekoh, Ansgar J Pommer, Lars Philipsen, Raik Bockelmann, Yanina Malykh, Harald Gollnick, Manuela Friedenberger, Marcus Bode & Andreas W M Dress

doi:10.1038/nbt1250

Abstract | Full Text | PDF

See also: News and Views by Murphy

Letters

Human C5aR knock-in mice facilitate the production and assessment of anti-inflammatory monoclonal antibodies pp1279 - 1284

Hyun Lee, David Zahra, Alexis Vogelzang, Rebecca Newton, Jenny Thatcher, Annie Quan, Trina So, Jorg Zwirner, Frank Koentgen, Soren B Padkjaer, Fabienne Mackay, Peter L Whitfeld & Charles R Mackay

doi:10.1038/nbt1248

Abstract | Full Text | PDF

See also: News and Views by Wang

A probability-based approach for high-throughput protein phosphorylation analysis and site localization pp1285 - 1292

Sean A Beausoleil, Judit Villen, Scott A Gerber, John Rush & Steven P Gygi

doi:10.1038/nbt1240

Abstract | Full Text | PDF

See also: News and Views by Jensen

Erratum

Erratum: High-resolution computational models of genome binding events p1293

Yuan Qi, Alex Rolfe, Kenzie D MacIsaac, Georg K Gerber, Dmitry Pokholok, Julia Zeitlinger, Timothy Danford, Robin D Dowell, Ernest Fraenkel, Tommi S Jaakkola, Richard A Young & David K Gifford

doi:10.1038/nbt1006-1293a

Full Text | PDF

Corrigenda

Corrigendum: Tumor antigen[mdash]specific induction of transcriptionally targeted retroviral vectors from chimeric immune receptor[mdash]modified T cells p1293

John Chester, Anja Ruchatz, Michael Gough, Marka Crittenden, Heung Chong, Francois Loic-Cosset, Rosa Maria Diaz, Kevin Harrington, Luis Alvarez-Vallina & Richard Vile

doi:10.1038/nbt1006-1293b

Full Text | PDF

Corrigendum: Integrative model of the response of yeast to osmotic shock p1293

Edda Klipp, Bodil Nordlander, Roland Kruger, Peter Gennemark & Stefan Hohmann

doi:10.1038/nbt1006-1293c

Full Text | PDF

Naturejobs

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Careers and Recruitment

The hardest hire: today's chief medical officer pp1295 - 1296

Mari Paul

doi:10.1038/nbt1006-1295

Abstract | Full Text | PDF

People

People p1298

doi:10.1038/nbt1006-1298

Full Text | PDF

Top

MicroArray Quality Control

Nature Biotechnology is proud to present a special reprint supplement on the MicroArray Quality Control consortium sponsored by FDA, EPA, NCI and Agilent. The study provides a clear and statistically sound picture of reproducibility and reliability of seven different microarray gene expression analysis platforms.

For more information visit: www.nature.com/naturebiotechnology

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| Associate Director | | Biotechnology|Cancer Research / Oncology|Drug Discovery|Molecular Biology | | Genentech | | South San Francisco, CA United States
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| Scientist-Immunology Diagnostics | | Bioinformatics|Biotechnology|Drug Discovery|Immunology | | Genentech | | South San Francisco, CA United States
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