Subject: Drug [email-masked] 28 July 2006

From: "Drug Discovery"<[email-masked]>
Date: Fri, 28 Jul 2006 06:58:19 -0400 (EDT)

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28 July 2006 Issue

Horizon Symposia

News

Research highlights

Research & reviews

Market analysis

Naturejobs drug discovery

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Join us in Boston!

Nature Chemical Biology Annual Symposium: The Chemical Biology of the Cell.
Date: 10-11 November 2006
Venue: Museum of Science, Boston, MA

Focusing on the frontier of in vivo chemical biology, the Symposium will explore how chemists and biologists are contributing concepts and tools to our understanding of the molecular basis of cell biology. In a series of five scientific sessions across two days, an international panel of speakers will examine cell biology "from the inside-out".

For complete programme, list of speakers and registration details go to:

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| News |

Cancer wonder-drug hits the heart
Spotlight falls on lasting effects of Gleevec.

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Clinical-use stem cells made in Singapore
Lines designed for safe use in humans make their debut.

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Trial blazers
The drug industry may be going through lean times, as new candidates have to clear ever-higher safety hurdles. But this gives scientists who can steer a drug through clinical trials a head start in the job market.

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Break with tradition
Traditional medicine has spent decades in the wings of pharmacology. Now India is pushing it to centre stage.

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more news

| Research highlights |

Antibacterial drugs: new antibiotic on the horizon?
A return to investigating natural products as a source of antimicrobials.

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Neurodegenerative disorders: hunting for huntingtin modification
New insight into the pathogenesis of Huntington's disease.

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Epidemiology: a rock and a hard place
Why a rare cancer is responsible for half the deaths in Turkish villages.

more research highlights

| Market analysis |

Biosimilars: initial excitement gives way to reality
How the market will evolve after the approval of the first biosimilars.

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Varenicline
First-in-class drug approved for smoking cessation.

more market analysis articles

| Research & reviews |

Drug discovery in the ubiquitin–proteasome system
Therapeutic opportunities for diseases such as cancer and neurodegenerative disorders.

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Cell type–specific delivery of sirnas with aptamer-sirna chimeras
Technology aims to improve targeted delivery of RNA-interference-based drugs.

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Dynamic imaging of the immune system: progress, pitfalls and promise
Advances in light microscopy have allowed direct visualization of immune-cell behaviour in living animals.

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Enzymatic activation of voltage-gated potassium channels
Channel activators becoming more important in clinical pharmacology.

more research & reviews

| Naturejobs drug discovery |

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Career Path: Frank L. Douglas
Why the former pharma executive thinks the R&D model has to change.

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