Subject: Nature Reviews Neuroscience contents October 2006 Volume 7 Number 10 pp753 - 827

From: "Nature Reviews Neuroscience Alert"<[email-masked]>
Date: Fri, 22 Sep 2006 08:53:28 -0400 (EDT)

TABLE OF CONTENTS

October 2006 Volume 7 Number 10

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In this issue
Research Highlights
Reviews
Perspectives
Correspondence
Author Reply

Also this month
Featured article:
Non-conducting functions of voltage-gated ion channels
Leonard K. Kaczmarek

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From the editors
p753 | 10.1038/nrn2017

RESEARCH HIGHLIGHTS

Top

Neurophysiology: Via ferrata - the iron way
Daniel McGowan
p754 | 10.1038/nrn2014

Learning and memory: Neurotrypsin down memory lane
Rachel Jones
p755 | 10.1038/nrn2015

IN BRIEF
Neurogenetics | Synaptic plasticity | Behavioural neuroscience
p755 | 10.1038/nrn2019

Neurodegenerative diseases: Perils of ageing
Asher Mullard
p756 | 10.1038/nrn2010

Development: Glutamate signals growth
Daniel McGowan
p756 | 10.1038/nrn2013

IN THE NEWS
Silent Communication
Tom Frost
p756 | 10.1038/nrn2021

IN BRIEF
Neurotransmitters | Neurogenesis | Neurodegenerative diseases
p757 | 10.1038/nrn2020

Neurodegenerative diseases: A sticky subject
Katherine Whalley
p758 | 10.1038/nrn2011

Development: Channels show the way
Daniel McGowan
p758 | 10.1038/nrn2016

Psychiatric disorders: ProTREKtion against depression
Edward Wawrzynczak
p759 | 10.1038/nrn2018

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REVIEWS

Top

Non-conducting functions of voltage-gated ion channels
Leonard K. Kaczmarek
p761 | 10.1038/nrn1988
Voltage-gated ion channels are traditionally considered to solely mediate ion flux. New evidence is emerging that these channels also have important roles in various biological processes that are independent of ion conduction, including neuronal signalling, cell adhesion and gene transcription.
Abstract | Full Text | PDF

Article series: Signalling in Development
Morphogen to mitogen: the multiple roles of hedgehog signalling in vertebrate neural development
Marc Fuccillo, Alexandra L. Joyner & Gord Fishell
p772 | 10.1038/nrn1990
The role of sonic hedgehog as a morphogen involved in establishing ventral cell identity in the CNS is well known. Fishell and colleagues outline the current understanding of the molecular pathways involved in patterning and describe several recently identified and unrelated roles for hedgehog signalling.
Abstract | Full Text | PDF

Histone deacetylase inhibitors as therapeutics for polyglutamine disorders
Rachel Butler & Gillian P. Bates
p784 | 10.1038/nrn1989
An important pathological feature of polyglutamine repeat diseases involves abnormal interactions between the mutant protein and histone-modifying enzymes, leading to transcriptional dysregulation. Inhibition of these enzymes is therefore a promising therapeutic strategy for Huntington's disease and other polyglutamine repeat disorders.
Abstract | Full Text | PDF

Cancer pain and its impact on diagnosis, survival and quality of life
Patrick W. Mantyh
p797 | 10.1038/nrn1914
Cancer induces pain, which often leads to the diagnosis of disease. Mantyh discusses how understanding the mechanisms involved in cancer pain and chemotherapy-induced sensory neuropathy, also associated with pain, might improve the survival and quality of life of cancer patients.
Abstract | Full Text | PDF

PERSPECTIVES

Top

ESSAY
Brain plasticity and mental processes: Cajal again
Javier DeFelipe
p811 | 10.1038/nrn2005
It is 100 years since Cajal shared, with Golgi, the Nobel Prize for Physiology or Medicine. Despite the recognition Cajal received for his pioneering studies on the functional organization of the CNS, his fundamental observations on plasticity are less well-known.
Abstract | Full Text | PDF | Supplementary information

OPINION
Intermediate phenotypes and genetic mechanisms of psychiatric disorders
Andreas Meyer-Lindenberg & Daniel R. Weinberger
p818 | 10.1038/nrn1993
Using schizophrenia as an example, Meyer-Lindenberg and Weinberger review the effectiveness of the intermediate phenotype concept for characterizing the neural systems affected by risk gene variants, with a view to elucidating mechanistic aspects of brain function implicated in psychiatric disease.
Abstract | Full Text | PDF

CORRESPONDENCE

Top

Correspondence: What gets filled-in during filling-in?
Frans W. Cornelissen & Tony Vladusich
Published online: 01 October 2006
10.1038/nrn1869-c1
Full Text | PDF

AUTHOR REPLY

Top

Author Reply: Activation of the primary visual cortex (V1) related to surface brightness
Hidehiko Komatsu
Published online: 01 October 2006
10.1038/nrn1869-c2
Full Text | PDF

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