Subject: Nature Genetics Contents: August 2006 Volume 38 pp. 851 - 957

From: "Nature Genetics"<[email-masked]>
Date: Thu, 27 Jul 2006 16:50:16 -0400 (EDT)

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August 2006, Volume 38 No 8

| Editorial

| Correspondence

| News and Views

| Research Highlights

| Brief Communications

| Articles

| Letters

| Erratum

| Corrigendum

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Editorial

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The germinating seed of Arab genomics p851

doi:10.1038/ng0806-851

Abstract | Full Text | PDF

Correspondence

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TranscriptSNPView: a genome-wide catalog of mouse coding variation p853

Fiona Cunningham, Daniel Rios, Mark Griffiths, James Smith, Zemin Ning, Tony Cox, Paul Flicek, Pablo Marin-Garcin, Javier Herrero, Jane Rogers, Louise van der Weyden, Allan Bradley, Ewan Birney & David J Adams

doi:10.1038/ng0806-853a

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Has the chimpanzee Y chromosome been sequenced? pp853 - 854

Jennifer F Hughes, Helen Skaletsky, Steve Rozen, Richard K Wilson & David C Page

doi:10.1038/ng0806-853b

Full Text | PDF

Reply to "Has the chimpanzee Y chromosome been sequenced?" pp854 - 855

Yoko Kuroki, Todd D Taylor, Hideki Noguchi, Takehiko Ito, Atsushi Toyoda, Yoshiyuki Sakaki & Asao Fujiyama

doi:10.1038/ng0806-854

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Normalization procedures and detection of linkage signal in genetical-genomics experiments pp855 - 856

Rohan B H Williams, Chris J Cotsapas, Mark J Cowley, Eva Chan, David J Nott & Peter F R Little

doi:10.1038/ng0806-855

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Reply to "Normalization procedures and detection of linkage signal in genetical-genomics experiments" pp856 - 858

Elissa J Chesler, Leonid Bystrykh, Gerald de Haan, Michael P Cooke, Andrew Su, Kenneth F Manly & Robert W Williams

doi:10.1038/ng0806-856

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Reply to "Normalization procedures and detection of linkage signal in genetical-genomics experiments" pp858 - 859

Enrico Petretto, Jonathan Mangion, Stuart A Cook, Timothy J Aitman, Michal Pravenec, Herbert Schulz, Judith Fischer & Norbert Hubner

doi:10.1038/ng0806-858

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Animal research and the search for understanding p859

Sandy Thomas

doi:10.1038/ng0806-859

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News and Views

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Closing in on complex traits pp861 - 862

Ariel Darvasi

doi:10.1038/ng0806-861

Abstract | Full Text | PDF

See also: Article by Valdar et al.

From worm genetic networks to complex human diseases pp862 - 863

Howard Bussey, Brenda Andrews & Charles Boone

doi:10.1038/ng0806-862

Abstract | Full Text | PDF

See also: Article by Lehner et al.

Context-dependent cancer risk pp864 - 865

Kent W Hunter

doi:10.1038/ng0806-864

Abstract | Full Text | PDF

See also: Letter by To et al.

The difference between simple and complex leaves pp865 - 866

Elizabeth A Kellogg

doi:10.1038/ng0806-865

Abstract | Full Text | PDF

See also: Letter by Hay and Tsiantis

Nucleic acid by-products and chronic inflammation pp866 - 867

Marta E Alarcon-Riquelme

doi:10.1038/ng0806-866

Abstract | Full Text | PDF

See also: Article by Crow et al.  | Letter by Crow et al.

Touching base p869

doi:10.1038/ng0806-869

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Research Highlights

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Research Highlights p871

doi:10.1038/ng0806-871

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Brief Communications

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ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles pp873 - 875

Anthony Renwick, Deborah Thompson, Sheila Seal, Patrick Kelly, Tasnim Chagtai, Munaza Ahmed, Bernard North, Hiran Jayatilake, Rita Barfoot, Katarina Spanova, Lesley McGuffog, D Gareth Evans, Diana Eccles, Douglas F Easton, Michael R Stratton, The Breast Cancer Susceptibility Collaboration (UK) & Nazneen Rahman

doi:10.1038/ng1837

Abstract | Full Text | PDF

Epigenetic asymmetry of imprinted genes in plant gametes pp876 - 878

Jose F Gutierrez-Marcos, Liliana M Costa, Mauro Dal Pra, Stefan Scholten, Erhard Kranz, Pascual Perez & Hugh G Dickinson

doi:10.1038/ng1828

Abstract | Full Text | PDF

Articles

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Genome-wide genetic association of complex traits in heterogeneous stock mice pp879 - 887

William Valdar, Leah C Solberg, Dominique Gauguier, Stephanie Burnett, Paul Klenerman, William O Cookson, Martin S Taylor, J Nicholas P Rawlins, Richard Mott & Jonathan Flint

doi:10.1038/ng1840

Abstract | Full Text | PDF

See also: News and Views by Darvasi

Candidate lung tumor susceptibility genes identified through whole-genome association analyses in inbred mice pp888 - 895

Pengyuan Liu, Yian Wang, Haris Vikis, Anna Maciag, Daolong Wang, Yan Lu, Yan Liu & Ming You

doi:10.1038/ng1849

Abstract | Full Text | PDF

Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways pp896 - 903

Ben Lehner, Catriona Crombie, Julia Tischler, Angelo Fortunato & Andrew G Fraser

doi:10.1038/ng1844

Abstract | Full Text | PDF

See also: News and Views by Bussey et al.

Principal components analysis corrects for stratification in genome-wide association studies pp904 - 909

Alkes L Price, Nick J Patterson, Robert M Plenge, Michael E Weinblatt, Nancy A Shadick & David Reich

doi:10.1038/ng1847

Abstract | Full Text | PDF

Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutieres syndrome and mimic congenital viral brain infection pp910 - 916

Yanick J Crow, Andrea Leitch, Bruce E Hayward, Anna Garner, Rekha Parmar, Elen Griffith, Manir Ali, Colin Semple, Jean Aicardi, Riyana Babul-Hirji, Clarisse Baumann, Peter Baxter, Enrico Bertini, Kate E Chandler, David Chitayat, Daniel Cau, Catherine Dery, Elisa Fazzi, Cyril Goizet, Mary D King, Joerg Klepper, Didier Lacombe, Giovanni Lanzi, Hermione Lyall, Maria Luisa Martinez-Frias, Michele Mathieu, Carole McKeown, Anne Monier, Yvette Oade, Oliver W Quarrell, Christopher D Rittey, R Curtis Rogers, Amparo Sanchis, John B P Stephenson, Uta Tacke, Marianne Till, John L Tolmie, Pam Tomlin, Thomas Voit, Bernhard Weschke, C Geoffrey Woods, Pierre Lebon, David T Bonthron, Chris P Ponting & Andrew P Jackson

doi:10.1038/ng1842

Abstract | Full Text | PDF

See also: News and Views by Alarcon-Riquelme

Letters

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Mutations in the gene encoding the 3[prime]-5[prime] DNA exonuclease TREX1 cause Aicardi-Goutieres syndrome at the AGS1 locus pp917 - 920

Yanick J Crow, Bruce E Hayward, Rekha Parmar, Peter Robins, Andrea Leitch, Manir Ali, Deborah N Black, Hans van Bokhoven, Han G Brunner, Ben C Hamel, Peter C Corry, Frances M Cowan, Suzanne G Frints, Joerg Klepper, John H Livingston, Sally Ann Lynch, Roger F Massey, Jean Francois Meritet, Jacques L Michaud, Gerard Ponsot, Thomas Voit, Pierre Lebon, David T Bonthron, Andrew P Jackson, Deborah E Barnes & Tomas Lindahl

doi:10.1038/ng1845

Abstract | Full Text | PDF

See also: News and Views by Alarcon-Riquelme

A functional SNP in PSMA6 confers risk of myocardial infarction in the Japanese population pp921 - 925

Kouichi Ozaki, Hiroshi Sato, Aritoshi Iida, Hiroya Mizuno, Takahiro Nakamura, Yoshinari Miyamoto, Atsushi Takahashi, Tatsuhiko Tsunoda, Shiro Ikegawa, Naoyuki Kamatani, Masatsugu Hori, Yusuke Nakamura & Toshihiro Tanaka

doi:10.1038/ng1846

Abstract | Full Text | PDF

A functional switch from lung cancer resistance to susceptibility at the Pas1 locus in Kras2 LA2 mice pp926 - 930

Minh D To, Jesus Perez-Losada, Jian-Hua Mao, Jeff Hsu, Tyler Jacks & Allan Balmain

doi:10.1038/ng1836

Abstract | Full Text | PDF

See also: News and Views by Hunter

Probing long-distance regulatory interactions in the Drosophila melanogaster bithorax complex using Dam identification pp931 - 935

Fabienne Cleard, Yuri Moshkin, Francois Karch & Robert K Maeda

doi:10.1038/ng1833

Abstract | Full Text | PDF

RNA interference machinery influences the nuclear organization of a chromatin insulator pp936 - 941

Elissa P Lei & Victor G Corces

doi:10.1038/ng1850

Abstract | Full Text | PDF

The genetic basis for differences in leaf form between Arabidopsis thaliana and its wild relative Cardamine hirsuta  pp942 - 947

Angela Hay & Miltos Tsiantis

doi:10.1038/ng1835

Abstract | Full Text | PDF

See also: News and Views by Kellogg

A naturally occurring epigenetic mutation in a gene encoding an SBP-box transcription factor inhibits tomato fruit ripening pp948 - 952

Kenneth Manning, Mahmut Tor, Mervin Poole, Yiguo Hong, Andrew J Thompson, Graham J King, James J Giovannoni & Graham B Seymour

doi:10.1038/ng1841

Abstract | Full Text | PDF

Emergence of a new disease as a result of interspecific virulence gene transfer pp953 - 956

Timothy L Friesen, Eva H Stukenbrock, Zhaohui Liu, Steven Meinhardt, Hua Ling, Justin D Faris, Jack B Rasmussen, Peter S Solomon, Bruce A McDonald & Richard P Oliver

doi:10.1038/ng1839

Abstract | Full Text | PDF

Erratum

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Erratum: Identification of the gene responsible for methylmalonic aciduria and homocystinuria, cblC type p957

Jordan P Lerner-Ellis, Jamie C Tirone, Peter D Pawelek, Carole Dore, Janet L Atkinson, David Watkins, Chantal F Morel, T Mary Fujiwara, Emily Moras, Angela R Hosack, Gail V Dunbar, Hana Antonicka, Vince Forgetta, C Melissa Dobson, Daniel Leclerc, Roy A Gravel, Eric A Shoubridge, James W Coulton, Pierre Lepage, Johanna M Rommens, Kenneth Morgan & David S Rosenblatt

doi:10.1038/ng0806-957a

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Corrigendum

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Corrigendum: PLA2G6, encoding a phospholipase A2, is mutated in neurodegenerative disorders with high brain iron p957

Neil V Morgan, Shawn K Westaway, Jenny E V Morton, Allison Gregory, Paul Gissen, Scott Sonek, Hakan Cangul, Jason Coryell, Natalie Canham, Nardo Nardocci, Giovanna Zorzi, Shanaz Pasha, Diana Rodriguez, Isabelle Desguerre, Amar Mubaidin, Enrico Bertini, Richard C Trembath, Alessandro Simonati, Carolyn Schanen, Colin A Johnson, Barbara Levinson, C Geoffrey Woods, Beth Wilmot, Patricia Kramer, Jane Gitschier, Eamonn R Maher & Susan J Hayflick

doi:10.1038/ng0806-957b

Full Text | PDF

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