Subject: Nature Reviews Neuroscience Contents August 2006 Volume 7 Number 8, pp 591 - 678

From: "Nature Reviews Neuroscience"<[email-masked]>
Date: Fri, 21 Jul 2006 12:45:55 -0400 (EDT)

TABLE OF CONTENTS

August 2006 Volume 7 Number 8

Impact Factor 20.951 *

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In this issue
Research Highlights
Focus on: Nerve regeneration
Reviews
Focus on: Nerve regeneration
Perspective
Reviews
Correspondence

Also this month
Featured article:
Glial inhibition of CNS axon regeneration
Glenn Yiu and Zhigang He

Nature Reviews Neuroscience Focus on Nerve Regeneration — August 2006
Free online access

This Focus will cover changes at the molecular, cellular and circuitry levels in response to injuries to the central nervous system in adulthood. These changes enable the understanding of underlying mechanisms and the development of appropriate therapeutic strategies to enable functional recovery.

Access the Focus FREE online with support from the Wings for Life Spinal Cord Research Foundation.

From the Editors
p591 | 10.1038/nrn1985

RESEARCH HIGHLIGHTS

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Download Research Highlights in PDF (957K)

Cell biology of the neuron: Degrading Id
p592 | 10.1038/nrn1978

Neurotransmission: Clamping down on exocytosis
p593 | 10.1038/nrn1975

Neurophysiology: Under the influence
p593 | 10.1038/nrn1983

Pain: The frequency for pain
Published online: 12 July 2006
p594 | 10.1038/nrn1976

Nerve regeneration: A dual role for reactive astrocytes
p594 | 10.1038/nrn1977

IN BRIEF
Development | Synaptic Plasticity | Neurodegenerative Disorders | Behavioural Neuroscience
p595 | 10.1038/nrn1984

Nerve Regeneration: A strain on regeneration
p596 | 10.1038/nrn1972

Cognitive neuroscience: Cultural differences
Published online: 12 July 2006
p596 | 10.1038/nrn1980

Cognitive neuroscience: Pause for thought
p597 | 10.1038/nrn1981

Synaptic plasticity: Branching out with WNT
Published online: 12 July 2006
p598 | 10.1038/nrn1979

Development: Mapping cerebellar development
p598 | 10.1038/nrn1982

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Focus on: Nerve regeneration

REVIEWS

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Can regenerating axons recapitulate developmental guidance during recovery from spinal cord injury?
Noam Y. Harel & Stephen M. Strittmatter
p603 | 10.1038/nrn1957
During development, precisely coordinated processes allow the formation of complex neural circuitry, but after CNS injury in adult mammals, functional circuits fail to reform. Recent work indicates that the recapitulation of developmental processes will be advantageous for successful functional recovery.
Abstract | Full Text | PDF | Supplementary information

Glial inhibition of CNS axon regeneration
Glenn Yiu & Zhigang He
p617 | 10.1038/nrn1956
Glial inhibition — involving myelin inhibitors and astroglial scarring — represents one of the major barriers to regeneration after CNS injury. Knowledge of the molecular mechanisms of these processes could be crucial for developing therapies to promote axon regeneration and plasticity.
Abstract | Full Text | PDF

Therapeutic interventions after spinal cord injury
Sandrine Thuret, Lawrence D. F. Moon & Fred H. Gage
p628 | 10.1038/nrn1955
There is no known cure for spinal cord injury, although numerous promising cellular, molecular and rehabilitative strategies are being tested in animal models and clinical trials. Emerging findings suggest that a combination of therapies will lead to optimal functional outcome.
Abstract | Full Text | PDF

Focus on: Nerve regeneration

PERSPECTIVE

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OPINION
Spinal cord repair strategies: why do they work?
Elizabeth J. Bradbury & Stephen B. McMahon
p644 | 10.1038/nrn1964
Although potential therapeutic strategies for spinal cord injury are emerging, the mechanisms underlying functional recovery are unclear. Recent work emphasizes the contribution of axon regeneration and plasticity, yet their involvement, and that of less well-explored processes, remains to be established.
Abstract | Full Text | PDF

REVIEWS

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Molecular approaches to brain asymmetry and handedness
Tao Sun & Christopher A. Walsh
p655 | 10.1038/nrn1930
The human left and right hemispheres have distinct functions. Sun and Walsh discuss recent genetic, imaging and neurological studies in an attempt to unravel the molecular mechanisms of brain asymmetry and handedness and to understand their evolutionary underpinning.
Abstract | Full Text | PDF

Path integration and the neural basis of the 'cognitive map'
Bruce L. McNaughton et al.
p663 | 10.1038/nrn1932
Mammals keep track of relative position and orientation by integrating self-motion cues. McNaughton and colleagues discuss the neurobiological evidence for a synaptic matrix capable of performing this task, and propose a model for how this neuronal network might arise developmentally.
Abstract | Full Text | PDF

CORRESPONDENCE

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Correspondence: Interval timing
J. E. R. Staddon & J. J. Higa
Published online: 01 August 2006
p | 10.1038/nrn1764-c1
Full Text | PDF

Neuropsychopharmacology, official publication of the American College of Neuropsychopharmacology, publishes the highest quality original research advancing our understanding of the brain and behavior. Visit www.neuropsychopharmacology.org to read a full issue FREE online now.

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*Journal Citation Reports, Thomson, 2006

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